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FAST DISSOLVING TABLET OF METOPROLOL TARTRATE USING SUPERDIS IBD

LAP LAMBERT ACADEMIC PUBLISHIN
06 / 2012
9783659150944
Inglés

Sinopsis

Metoprolol Tartrate is a ?-blocker drug indicated for the treatment of angina, prevention of myocardial infarction, Essential hypertension, It has low bioavailability of about 40% due to hepatic metabolism. The purpose of this research was to improve the bioavailability by preparing a fast dissolving tablet using superdisintegrants method. Because pregastric absorption of drug improves bioavailability, gives rapid onset of action when needed.